What we do
Innovation
Sustainable Innovation through non-invasive methods to understand biomolecular structures, biochemical interactions of biological and disease pathways
Discovery Solutions
Making structural biology accessible for genomics and proteomics to drug development pipelines and life sciences research
End-to-End Services
Expedition by reduced data collection and processing time with unbiased machine learning and 3D reconstruction of biological macromolecules or subcellular complexes
Unmatched Throughput
With our novel reproducible approach, we achieve unparalleled maximum throughput with cost and time efficiency
Driving Research
Enabling biochemists, healthcare research professionals and hospitals characterize biomarkers, protein complexes and viruses
Structural Solutions
Decipher functional insights through high-resolution structures with precision
“When the world is in trouble, chemistry comes to the rescue!”
– Carolyn Bertozzi, Nobel Prize in Chemistry 2022
Unlock the mysteries of biomolecular architecture
- Experience the dynamic molecular architectures and conformations of samples first-hand.
- Shape the future of molecular discovery with ease and ensure reproducibility.
- Don’t stop at biochemical functional assays! Visualize the structures and contribute to scientific discovery and knowledge
- Showcase your story by exploring and characterizing the structures.
Capture heterogeneity
- Structures from homogeneous and heterogeneous samples.
- Tagged or non-tagged protein complexes, protein-ligand complexes, biomolecules and viruses.
- Case studies celebrating unbiased native biomolecular architectures and subcomplexes.
Our comprehensive expertise and services cater to a diverse needs of biochemists, cell biologists, drug developers, life sciences researchers to vaccinologists.
Precision structure determination now accessible, affordable, reproducible and scalable
Type I restriction modification system (EcoR124I)
The first unbiased electron density map of the type I restriction modification system EcoR124I that enables bacteria fight the invading viral genome. The pentameric complex comprises two restriction endonuclease subunits, two methylation subunits and one specificity subunit.
EcoR124I Methyltransferase
The first unbiased electron density map of the Mtase trimeric complex of EcoR124I. This complex forms when two methylation subunits (shown as deep pink) bind to the specificity subunit (shown as turquoise). The HsdM subunit homes the catalytic site for DNA methylation as well as the binding site for the methyl donor and restriction cofactor S-AdoMet to perform its main function of DNA modification by transferring a methyl group from the donor AdoMet.
Active fully resolved HsdR of type I restriction-modification subunit
The HsdR subunit of the EcoR124I Type I restriction-modification system is crucial for the ATP-dependent translocation and subsequent cleavage of unmethylated foreign DNA, utilizing energy from ATP hydrolysis to translocate along the DNA and introduce double-strand breaks at distant sites. The HsdR subunit’s endonuclease activity is highly regulated through interactions with the HsdS and HsdM subunits, forming a functional holoenzyme that ensures only foreign DNA is targeted.
Meet our team
Team MolVerse comprises of qualified and experienced resources with 5-12+ years of experience in their respective fields. We believe that to be able to understand the client needs, the team has the right blend of knowledge and attitude. Our team members are mostly from Sci-Tech and business/small enterprise management background and experience.
Pradeep Hiriyur Nagaraj
Founder & CEO
Tapan Pancholi
Co-founder & CTO
Ramesh Tata Anantha (Gupta)
Co-founder & COO